ABSTRACT
Cytomegalovirus [CMV] pneumonia is one of the most important infections in immunocompromised host. Immunosuppressive therapy plays a major role in reactivation of CMV. The patient was a 56-year old lady, known case of chronic lymphocytic leukemia [CLL], had been taking prednisolone and chlorambucil, who presented with dyspnea and productive cough. After bronchoalveolar lavage [BAL], transbronchial lung biopsy [TBLB] and CT-guided biopsy, CMV pneumonia was diagnosed. CMV should be suspected as a cause of pneumonia in immunocompromised patient and diagnosis may require invasive procedures
Subject(s)
Humans , Female , Cytomegalovirus Infections , Pneumonia , Immunocompromised Host , Immunosuppression Therapy/adverse effects , Leukemia, Lymphocytic, Chronic, B-Cell , Prednisolone/adverse effects , Prednisolone , Chlorambucil/adverse effects , ChlorambucilABSTRACT
Kaposi's sarcoma is one of malignancies that is most seen in HIV positive or immunocompromised patients. Kaposi's sarcoma typically involves the skin. We present a HIV negative, 31-year-old Iranian woman from Tehran with Kaposi's sarcoma associated with corticosteroid use
Subject(s)
Humans , Adult , Female , Dexamethasone/adverse effects , Herpesvirus 8, HumanABSTRACT
Kartagener's syndrome is a rare genetic disorder, which is mostly inherited as an autosomal recessive trait. There are 4 genes with a proven pathogenetic role in Kartagener's syndrome. It results from ciliary dysfunction and is commonly characterized by sinusitis, male infertility, hydrocephalus, and situs inversus. Since Kartagener's syndrome causes deficiency or even stasis of the transport of secretions throughout the respiratory tract, it favors the growth of viruses and bacteria. As a result, patients have lifelong chronic and recurrent infections, typically suffering from bronchitis, pneumonia, hemoptysis, sinusitis, and infertility. We present a 27-year-old woman, a case of Kartagene's syndrome, with multiple pulmonary abscesses. Evaluation of sputum and tracheal secretions revealed Pseudomonas aeroginosa. Antibiotics were started and respiratory symptoms resolved and the patient was discharged in good general condition. As a conclusion, prompt and appropriate treatment of respiratory infections can minimize irreversible lung damage in such cases